Mike,

Thank you for the insight.  That is actually helpful,  a previous set of instructions did not inform me the the KeepConn was limited to 65535.  That aside I did have group policies in place to create the registry entries for these items but they may not have been working.

In context, what is happening is a customer is running a report and the report takes LONG to run,  about 25 minutes (personally I don't think there is any excuse for an application report to take 25 minutes but that is not terribly relevant).   The report spends most of its time displaying "sorting" in the toolbar. During this sorting time if there is no action on the drive it could possibly disconnect under the default 10 minute value. 

Just seems odd that the application would be "sorting" and that would cause no network activity.  I think the user typically runs a second session of the application and runs other parts of the application while the report is being created.   I will review the registry on the workstation that runs these reports tomorrow and I will see if that makes any difference.  I will also look for those delayed write failures,  but there isn't really much "writing" going on in this process.

I apologize preemptively for this but I have receive almost no help from the application developer and was hoping someone here may have some more insight into what is going on with this application.  First off they are running PxPlus-2017 Pro Version 14.00 on a Windows 2019 Server.  The application generates an error frequently when running specific reports.   

The program appears to generate error 005
and shows

Unlock Region Failure
Likely hardware/network issue

The report is apparently working with a very large amount of data but I see no errors on the server side to speak of regarding a read error or any other data problem.   the application developer basically has washed their hands of it and says it is a hardware problem which I might believe if the system showed any signs of other problems but it does not.  Any guidance or direction would be highly appreciated if it is even possible with that limited information.